Address:

MRC Biostatistics Unit,
Institute of Public Health,
University Forvie Site,
Robinson Way,
Cambridge. UK.
CB2 0SR

Telephone Number:

Email Address:

Research Interests:

Currently I am leading the Cambridge Hub in Trials Methodology Research and working on issues in clinical trials. My main research interests are:

• Using information between phases to help adapt study designs for Psychiatry and Oncology trials;
• Multivariate modelling of nutrition trials both in dietary pattern analysis and combining information across fatty acid profiles;
• Bayesian modelling of kinetic data;
• Statistical programming using Stata;
• Genetic analysis to help identify subgroups of responders;
• Multiple imputation using hotdeck.

Selected Recent Publications:

J.M. Wason, A.P. Mander and S.G. Thompson (2011) Optimal multistage designs for randomised clinical trials with continuous outcomes. Stat. Med. DOI: 10.1002/sim.4421

J.M. Wason, A.P.Mander and T. Eisen (2011) Reducing sample sizes in two-stage phase II cancer trials by using continuous tumour shrinkage end-points. Eur J Cancer. 47(7):983-9.

A.P. Mander, J.M. Wason, M.J. Sweeting and S.G. Thompson (2011). Admissible two-stage designs for phase II cancer clinical trials that incorporate the expected sample size under the alternative hypothesis. Pharm. Stats. In press.

A.P. Mander and S.G. Thompson (2010) Two-stage designs optimal under the alternative hypothesis forphase II cancer clinical trials. Contemp. Clin. Trials. 31:572-578.

J.M.S. Wason and A.P. Mander (2010) Minimising the maximum sample size in two-stage designs for phase II clinical trials with continuous outcomes. J. Biopharm. Stat. In press.