Address:

MRC Biostatistics Unit,
Institute of Public Health,
University Forvie Site,
Robinson Way,
Cambridge. UK.
CB2 0SR

Telephone Number:

Email Address:

Research Interests:

Mathematical modelling and statistical inference of gene regulation. Inference of gene regulatory networks, dynamical systems, stochastic dynamical systems. Computational analysis of transcription factor binding.

Selected Recent Publications:

I. Pournara, L. Wernisch, Using Temporal Correlation in Factor Analysis for Reconstructing Transcription Factor Activities, EURASIP Journal on Bioinformatics and Systems Biology, Volume 2008, Article ID 172840, 12 pages, 2008

M. D. Reis, L. Wernisch, Estimating translational selection in Eukaryotic genomes, Mol Biol Evol 26(2):451-61, 2009

Y. Zhang, K.A. Hatch, L. Wernisch, J. Bacon, A Bayesian Change point model for differential gene expression patterns of the DosR regulon of Mycobacterium tuberculosis, BMC Genomics 9:87, 2008

J. Bacon, L.G. Dover, K.A. Hatch, Y. Zhang, J.M. Gomes, S. Kendall, L. Wernisch, N.G. Stoker, P.D. Butcher, G.S. Besra, P.D. Marsh, Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: identification of a novel wax ester, Microbiology 153:1435-44, 2007

K. Evans, S. Ott, A. Hansen, G. Koentges, L. Wernisch, A comparative study of S/MAR prediction tools, BMC Bioinformatics 8:71, 2007

I. Pournara, L. Wernisch, Factor analysis for gene regulatory networks and transcription factor activity profiles, BMC Bioinformatics 8:61, 2007