SummaryI joined the BSU in 2015 as a student on the 4-year Wellcome Trust Mathematical Genomics and Medicine PhD programme. My overall field of research is the development of statistical methods for analysing genomic data. One important aim of this field is to create more efficient medical treatment for complex diseases (such as cancer). The idea is to stratify treatment for patients based upon their individual genomic profile - an initiative known as precision medicine. My work is conducted under the supervision of Prof. Sylvia Richardson, Dr. Catalina Vallejos, and Dr. Gwenaël Leday.
PhD projectIn general, my project focuses upon exploring the interactions between biological molecules, how this information can then be used to infer properties of the underlying biological processes, and then how this relates to disease. Some challenges that I come across are:
- high-dimensional statistics, where sample estimates cannot be used
- integrating data-types that are heterogeneous both in biological meaning and format (e.g. continuous gene expression vs binary Hi-C)