The majority of biologic and small molecule drugs perturb protein targets to exert their effects. With the recent explosion in the availability of large-scale genetic association data, it is increasingly feasible to identify genetic variants that proxy the effect of perturbing a protein drug target. Such leverage of genetic data thus offers an efficient and cost-effective approach for identifying drug targets and studying their effects.
Our brand new short course on “Genetics in drug development” will provide theoretical and practical advice on using genetic data to:
- Identify drug targets
- Investigate the effects of drug target perturbation for different indications
- Explore potential adverse effects and repurposing potential for drug targets
- Identify biomarkers to explore drug efficacy in early stage clinical trials
- Identify population subgroups for which drug effects may vary
- Explore interactions between different drugs and exposures
The course is designed for all those interested in leveraging genetic data for drug development and investigation of drug effects, most notably:
- Employees of pharmaceutical companies
The course will be held online over one week and will consist of a series of four recorded video lectures, three live interactive sessions with practical examples, and participation in an online community that allows for questions to be posted on a live “chat” function that will be active for the duration of the course.
A basic understanding of genetic epidemiology and statistics is desirable, as is some familiarity with the drug development process. However, this is not essential, as these topics will be covered briefly during the course. Previous experience of using the R statistical software is also desirable, although not essential. All code for the practical examples used during the course will be provided for R.
For further details, click here.
To register, click here.
Please email any registration or other queries to: email@example.com