
Research theme(s): Causal Mechanisms
Role: Research Associate
Telephone number:
Email Address: elena.vigorito@mrc-bsu.cam.ac.uk
Role: Research Associate
Telephone number:
Email Address: elena.vigorito@mrc-bsu.cam.ac.uk
I obtained a PhD in immunology at the University of Barcelona, Spain, and worked for several years on gene regulation on the immune system at the Babraham Institute, UK. I joined Chris Wallace's group at the BSU in January 2017 to apply statistical and computational methods for further understanding causes of autoimmune diseases.
Selected Papers
- Vigorito E, Kuchenbaecker KB, Beesley J, […],Chenevix-Trench G, Antoniou AC. Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. PLoS One. 2016 Jul 27;11(7):e0158801.
- Nakagawa R, Leyland R, Meyer-Hermann M, Lu D, Turner M, Arbore G, Phan TG, Brink R, Vigorito E. MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis. J Clin Invest. 2016 Jan;126(1):377-88.
- Lu D, Nakagawa R, Lazzaro S, Staudacher P, Abreu-Goodger C, Henley T, Boiani S, Leyland R, Galloway A, Andrews S, Butcher G, Nutt SL, Turner M, Vigorito E. The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B celldifferentiation. J Exp Med. 2014 Oct 20;211(11):2183-98.
- Turner M, Galloway A, Vigorito E. Noncoding RNA and its associated proteins as regulatory elements of the immune system. Nat Immunol. 2014 Jun;15(6):484-91.