MRC Biostatistics Unit
DART: Design and Analysis of Randomised Trials
Telephone number:Email Address: james.wason@mrc-bsu.cam.ac.uk
Other Research Theme Collaborations: SOMX PREM
Person Overview
I am currently jointly appointed at the BSU, as a Programme Leader Track, and at Newcastle University, as a Professor of Biostatistics. I began my research career at the BSU in 2006 as a PhD student, working in statistical genetics. I then moved to working in statistical methods for improving clinical trials, starting as a Research Statistician in 2009, then a Senior Investigator Statistician in 2012. I was appointed as a Programme Leader Track in November 2015 working on clinical trials methodology within the Design and Analysis of Randomised Trials research theme at BSU.BSU Research Overview
My group's research focuses on statistical methods for next-generation clinical trials. This includes several areas of work that address the need for efficient clinical trials, both in academia and in the pharmaceutical industry. James Wason's personal pages Google Scholar page //Selected Papers
Wason J, Brocklehurst P, Yap C. (2019)When to keep it simple – adaptive designs are not always useful.BMC Medicine 17: 1-7
Pallmann P, Bedding A, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander A, Sydes M, Villar S, Wason, J, Weir C, Wheeler G, Yap C, Jaki T (2018)Adaptive designs in clinical trials: why use them, and how to run and report them
BMC medicine : 16(1), 29
Fonagy P et al (2018)Design of experiments for a confirmatory trial of precision medicine
Journal of Statistical Planning and Inference : 199, 179-187
Lee K and Wason J. (2019)Design of experiments for a confirmatory trial of precision medicine
Journal of Statistical Planning and Inference : 199, 179-187
Robertson D and Wason J. (2019)Familywise error rate control in multi-armed response-adaptive trials
Biometrics : E-published
Grayling, M., Wason, J. & Mander, A. (2017)Group sequential designs for stepped-wedge cluster randomised trials
Clinical Trials : E-published
Wason, J., Stallard, N., Bowden, J. & Jennison, C. (2017)A multi-stage drop-the-losers design for multi-arm clinical trials
Statistical Methods in Medical Research 26: 508-524
Wason, J. & Jenkins, M. (2016)Improving the power of clinical trials of rheumatoid arthritis by using data on continuous scales when analysing response rates: an application of the augmented binary method
Rheumatology 55: 1796-1802
Wason J (2015)OptGS – An R package for finding near-optimal group-sequential designs.
Journal of Statistical Software 66: 2
Wason J, Abraham J, Baird R, Gournaris J, Vallier A, Brenton J, Earl H, Mander A. (2015)A Bayesian adaptive design for biomarker trials with linked treatments
British Journal of Cancer 113: 699-705
Wason, J., Magirr, D., Law, M. & Jaki, T. ()Some recommendations for multi-arm multi-stage trials.
Statistical Methods in Medical Research : (ePub)
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