MRC Biostatistics UnitThe MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy
Our latest published papers are below
Mousa, A, Savva, GM, Mitnitski, A, Rockwood, K, Jagger, C, Brayne, C, Matthews, FE. 2018. Is frailty a stable predictor of mortality across time? Evidence from the Cognitive Function and Ageing Studies. Age Ageing :. PubMed PMID:29905755
Hofmann, I, Geer, MJ, Vögtle, T, Crispin, A, Campagna, DR, Barr, A, Calicchio, ML, Heising, S, van Geffen, JP, Kuijpers, MJE, Heemskerk, JWM, Eble, JA, Schmitz-Abe, K, Obeng, EA, Douglas, M, Freson, K, Pondarré, C, Favier, R, Jarvis, GE, Markianos, K, Turro, E, Ouwehand, WH, Mazharian, A, Fleming, MD, Senis, YA. 2018. Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice. Blood :. PubMed PMID:29898956
Dadaev, T, Saunders, EJ, Newcombe, PJ, Anokian, E, Leongamornlert, DA, Brook, MN, Cieza-Borrella, C, Mijuskovic, M, Wakerell, S, Olama, AAA, Schumacher, FR, Berndt, SI, Benlloch, S, Ahmed, M, Goh, C, Sheng, X, Zhang, Z, Muir, K, Govindasami, K, Lophatananon, A, Stevens, VL, Gapstur, SM, Carter, BD, Tangen, CM, Goodman, P, Thompson, IM Jr, Batra, J, Chambers, S, Moya, L, Clements, J, Horvath, L, Tilley, W, Risbridger, G, Gronberg, H, Aly, M, Nordström, T, Pharoah, P, Pashayan, N, Schleutker, J, Tammela, TLJ, Sipeky, C, Auvinen, A, Albanes, D, Weinstein, S, Wolk, A, Hakansson, N, West, C, Dunning, AM, Burnet, N, Mucci, L, Giovannucci, E, Andriole, G, Cussenot, O, Cancel-Tassin, G, Koutros, S, Freeman, LEB, Sorensen, KD, Orntoft, TF, Borre, M, Maehle, L, Grindedal, EM, Neal, DE, Donovan, JL, Hamdy, FC, Martin, RM, Travis, RC, Key, TJ, Hamilton, RJ, Fleshner, NE, Finelli, A, Ingles, SA, Stern, MC, Rosenstein, B, Kerns, S, Ostrer, H, Lu, YJ, Zhang, HW, Feng, N, Mao, X, Guo, X, Wang, G, Sun, Z, Giles, GG, Southey, MC, MacInnis, RJ, FitzGerald, LM, Kibel, AS, Drake, BF, Vega, A, Gómez-Caamaño, A, Fachal, L, Szulkin, R, Eklund, M, Kogevinas, M, Llorca, J, Castaño-Vinyals, G, Penney, KL, Stampfer, M, Park, JY et al.. 2018. Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants. Nat Commun 9:2256. PubMed PMID:29892050
Wheeler, GM. 2018. Incoherent dose-escalation in phase I trials using the escalation with overdose control approach. Stat Pap (Berl) 59:801-811. PubMed PMID:29875549
Sun, BB, Maranville, JC, Peters, JE, Stacey, D, Staley, JR, Blackshaw, J, Burgess, S, Jiang, T, Paige, E, Surendran, P, Oliver-Williams, C, Kamat, MA, Prins, BP, Wilcox, SK, Zimmerman, ES, Chi, A, Bansal, N, Spain, SL, Wood, AM, Morrell, NW, Bradley, JR, Janjic, N, Roberts, DJ, Ouwehand, WH, Todd, JA, Soranzo, N, Suhre, K, Paul, DS, Fox, CS, Plenge, RM, Danesh, J, Runz, H, Butterworth, AS. 2018. Genomic atlas of the human plasma proteome. Nature 558:73-79. PubMed PMID:29875488
Zanetti, D, Tikkanen, E, Gustafsson, S, Priest, JR, Burgess, S, Ingelsson, E. 2018. Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease: Addressing the Barker Hypothesis With Mendelian Randomization. Circ Genom Precis Med 11:e002054. PubMed PMID:29875125
Keogh, RH, Seaman, SR, Bartlett, JW, Wood, AM. 2018. Multiple imputation of missing data in nested case-control and case-cohort studies. Biometrics :. PubMed PMID:29870056
Willemsen, RH, Burling, K, Barker, P, Ackland, F, Dias, RP, Edge, J, Smith, A, Todd, J, Lopez, B, Mander, AP, Guy, C, Dunger, DB. 2018. Frequent Monitoring of C-peptide Levels in Newly Diagnosed Type 1 Subjects Using Dried Blood Spots Collected at Home. J. Clin. Endocrinol. Metab. :. PubMed PMID:29860430
Burgess, S, Zuber, V, Gkatzionis, A, Foley, CN. 2018. Modal-based estimation via heterogeneity-penalized weighting: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid. Int J Epidemiol :. PubMed PMID:29846613
Jenkins, V, Farewell, V, May, S, Catt, S, Matthews, L, Shilling, V, Dickson, J, Simcock, R, Fallowfield, L. 2018. Do drugs offering only PFS maintain quality of life sufficiently from a patient's perspective? Results from AVALPROFS (Assessing the 'VALue' to patients of PROgression Free Survival) study. Support Care Cancer :. PubMed PMID:29845422
Schooling, CM, Luo, S, Au Yeung, SL, Thompson, DJ, Karthikeyan, S, Bolton, TR, Mason, AM, Ingelsson, E, Burgess, S. 2018. Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation. Int. J. Cardiol. :. PubMed PMID:29804699
McMenamin, M, Berglind, A, Wason, JMS. 2018. Improving the analysis of composite endpoints in rare disease trials. Orphanet J Rare Dis 13:81. PubMed PMID:29788976
Wen, L, Seaman, SR. 2018. Semi-parametric methods of handling missing data in mortal cohorts under non-ignorable missingness. Biometrics :. PubMed PMID:29772074
Larsson, SC, Burgess, S, Michaëlsson, K. 2018. Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation study. BMC Med 16:68. PubMed PMID:29769070
Zhong, Y, Cook, RJ. 2018. The effect of omitted covariates in marginal and partially conditional recurrent event analyses. Lifetime Data Anal :. PubMed PMID:29767377
Sun, YQ, Brumpton, BM, Bonilla, C, Lewis, SJ, Burgess, S, Skorpen, F, Chen, Y, Nilsen, TIL, Romundstad, PR, Mai, XM. 2018. Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study. Eur. Respir. J. 51:. PubMed PMID:29748306
Chandran, V, Stecher, L, Farewell, V, Gladman, DD. 2018. Patterns of peripheral joint involvement in psoriatic arthritis-Symmetric, ray and/or row?. Semin. Arthritis Rheum. :. PubMed PMID:29724452
Gao, L, Calloway, R, Zhao, E, Brayne, C, Matthews, FE, Medical Research Council Cognitive Function and Ageing Collaboration. 2018. Accuracy of death certification of dementia in population-based samples of older people: analysis over time. Age Ageing :. PubMed PMID:29718074
Burgess, S, Foley, CN, Zuber, V. 2018. Inferring Causal Relationships Between Risk Factors and Outcomes from Genome-Wide Association Study Data. Annu Rev Genomics Hum Genet :. PubMed PMID:29709202
Morgan, SE, White, SR, Bullmore, ET, Vértes, PE. 2018. A Network Neuroscience Approach to Typical and Atypical Brain Development. Biol Psychiatry Cogn Neurosci Neuroimaging :. PubMed PMID:29703679
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We also have a repository of Reports, Published Material, Pre-prints and Technical Reports in our Additional Material webpage.