The MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy

Our latest published papers can be viewed using the following link

Grant, AJ, Burgess, S. 2021. Pleiotropy robust methods for multivariable Mendelian randomization. Stat Med :. PubMed PMID:34342032

Guldvik, IJ, Zuber, V, Braadland, PR, Grytli, HH, Ramberg, H, Lilleby, W, Thiede, B, Zucknick, M, Saatcioglu, F, Gislefoss, R, Kvåle, R, George, A, Grönberg, H, Wiklund, F, Neal, DE, Gnanapragasam, VJ, Taskén, KA, Mills, IG. 2020. Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification. Eur Urol Open Sci 21:51-60. PubMed PMID:34337468

Vithayathil, M, Carter, P, Kar, S, Mason, AM, Burgess, S, Larsson, SC. 2021. Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study. PLoS Med 18:e1003706. PubMed PMID:34324486

Larsson, SC, Lee, WH, Kar, S, Burgess, S, Allara, E. 2021. Assessing the role of cortisol in cancer: a wide-ranged Mendelian randomisation study. Br J Cancer :. PubMed PMID:34316022

Griffiths, GO, FitzGerald, R, Jaki, T, Corkhill, A, Reynolds, H, Ewings, S, Condie, S, Tilt, E, Johnson, L, Radford, M, Simpson, C, Saunders, G, Yeats, S, Mozgunov, P, Tansley-Hancock, O, Martin, K, Downs, N, Eberhart, I, Martin, JWB, Goncalves, C, Song, A, Fletcher, T, Byrne, K, Lalloo, DG, Owen, A, Jacobs, M, Walker, L, Lyon, R, Woods, C, Gibney, J, Chiong, J, Chandiwana, N, Jacob, S, Lamorde, M, Orrell, C, Pirmohamed, M, Khoo, S, AGILE investigators. 2021. AGILE: a seamless phase I/IIa platform for the rapid evaluation of candidates for COVID-19 treatment: an update to the structured summary of a study protocol for a randomised platform trial letter. Trials 22:487. PubMed PMID:34311777

Treasure, T, Farewell, V, Macbeth, F, Batchelor, T, Milosevic, M, King, J, Zheng, Y, Leonard, P, Williams, NR, Brew-Graves, C, Morris, E, Fallowfield, L, PulMiCC investigators. 2021. The Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) burden of care study: Analysis of local treatments for lung metastases and systemic chemotherapy in 220 patients in the PulMiCC cohort. Colorectal Dis :. PubMed PMID:34310835

Perry, BI, Upthegrove, R, Kappelmann, N, Jones, PB, Burgess, S, Khandaker, GM. 2021. Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study. Brain Behav Immun :. PubMed PMID:34280516

Bojke, L, Soares, MO, Claxton, K, Colson, A, Fox, A, Jackson, C, Jankovic, D, Morton, A, Sharples, LD, Taylor, A. 2021. Reference Case Methods for Expert Elicitation in Health Care Decision Making. Med Decis Making :272989X211028236. PubMed PMID:34271832

Walker, AS, Pritchard, E, House, T, Robotham, JV, Birrell, PJ, Bell, I, Bell, JI, Newton, JN, Farrar, J, Diamond, I, Studley, R, Hay, J, Vihta, KD, Peto, TE, Stoesser, N, Matthews, PC, Eyre, DW, Pouwels, KB, COVID-19 Infection Survey team. 2021. Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time. Elife 10:. PubMed PMID:34250907

Fang, W, Wang, Z, Giles, MB, Jackson, CH, Welton, NJ, Andrieu, C, Thom, H. 2021. Multilevel and Quasi Monte Carlo Methods for the Calculation of the Expected Value of Partial Perfect Information. Med Decis Making :272989X211026305. PubMed PMID:34231446

Grayling, MJ, Bigirumurame, T, Cherlin, S, Ouma, L, Zheng, H, Wason, JMS. 2021. Innovative trial approaches in immune-mediated inflammatory diseases: current use and future potential. BMC Rheumatol 5:21. PubMed PMID:34210348

Ellervik, C, Mora, S, Kuś, A, Åsvold, BO, Marouli, E, Deloukas, P, Sterenborg, RBTM, Teumer, A, Burgess, S, Sabater-Lleal, M, Huffman, J, Johnson, AD, Tregouet, DA, Smith, NL, Medici, M, DeVries, PS, Chasman, DI, Kjærgaard, AD. 2021. Effects of thyroid function on hemostasis, coagulation, and fibrinolysis: a Mendelian Randomization study. Thyroid :. PubMed PMID:34210154

Yuan, S, Carter, P, Mason, AM, Burgess, S, Larsson, SC. 2021. Coffee Consumption and Cardiovascular Diseases: A Mendelian Randomization Study. Nutrients 13:. PubMed PMID:34203356

Stallard, N, Hampson, L, Benda, N, Brannath, W, Burnett, T, Friede, T, Kimani, PK, Koenig, F, Krisam, J, Mozgunov, P, Posch, M, Wason, J, Wassmer, G, Whitehead, J, Williamson, SF, Zohar, S, Jaki, T. 2020. Efficient Adaptive Designs for Clinical Trials of Interventions for COVID-19. Stat Biopharm Res 12:483-497. PubMed PMID:34191981

Fang, S, Kirk, PDW, Bantscheff, M, Lilley, KS, Crook, OM. 2021. A Bayesian semi-parametric model for thermal proteome profiling. Commun Biol 4:810. PubMed PMID:34188175

Witte, F, Ruiz-Orera, J, Mattioli, CC, Blachut, S, Adami, E, Schulz, JF, Schneider-Lunitz, V, Hummel, O, Patone, G, Mücke, MB, Šilhavý, J, Heinig, M, Bottolo, L, Sanchis, D, Vingron, M, Chekulaeva, M, Pravenec, M, Hubner, N, van Heesch, S. 2021. A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion. Genome Biol 22:191. PubMed PMID:34183069

Bylund-Grenklo, T, Birgisdóttir, D, Beernaert, K, Nyberg, T, Skokic, V, Kristensson, J, Steineck, G, Fürst, CJ, Kreicbergs, U. 2021. Correction to: Acute and long-term grief reactions and experiences in parentally cancer-bereaved teenagers. BMC Palliat Care 20:99. PubMed PMID:34182982

Cherlin, S, Wason, JMS. 2021. Developing a predictive signature for two trial endpoints using the cross-validated risk scores method. Biostatistics :. PubMed PMID:34165151

Uribe, ML, Dahlhoff, M, Batra, RN, Nataraj, NB, Haga, Y, Drago-Garcia, D, Marrocco, I, Sekar, A, Ghosh, S, Vaknin, I, Lebon, S, Kramarski, L, Tsutsumi, Y, Choi, I, Rueda, OM, Caldas, C, Yarden, Y. 2021. TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis. Sci Signal 14:. PubMed PMID:34158398

Gkatzionis, A, Burgess, S, Conti, DV, Newcombe, PJ. 2021. Bayesian variable selection with a pleiotropic loss function in Mendelian randomization. Stat Med :. PubMed PMID:34155684

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Additional Material

We also have a repository of Reports, Published Material, Pre-prints and Technical Reports in our Additional Material webpage.