The MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy
Our latest published papers can be viewed using the following link
Jackson, CH. 2023. survextrap: a package for flexible and transparent survival extrapolation. BMC Med Res Methodol 23:282. PubMed PMID:38030986
Yuan, S, Xu, F, Zhang, H, Chen, J, Ruan, X, Li, Y, Burgess, S, Åkesson, A, Li, X, Gill, D, Larsson, SC. 2023. Proteomic insights into modifiable risk of venous thromboembolism and cardiovascular comorbidities. J Thromb Haemost :. PubMed PMID:38029854
Fagbamigbe, AF, Agrawal, U, Azcoaga-Lorenzo, A, MacKerron, B, Özyiğit, EB, Alexander, DC, Akbari, A, Owen, RK, Lyons, J, Lyons, RA, Denaxas, S, Kirk, P, Miller, AC, Harper, G, Dezateux, C, Brookes, A, Richardson, S, Nirantharakumar, K, Guthrie, B, Hughes, L, Kadam, UT, Khunti, K, Abrams, KR, McCowan, C. 2023. Clustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland. PLoS One 18:e0294666. PubMed PMID:38019832
Bird, SM. 2023. Opioid-related deaths and their counterpart by occurrence-era, age-group and co-implicated drugs: Scotland versus England and Wales. Br J Clin Pharmacol :. PubMed PMID:38009544
Rajasundaram, S, Zebardast, N, Mehta, P, Khawaja, AP, Warwick, A, Duchinski, K, Burgess, S, Gill, D, Segrè, AV, Wiggs, J. 2023. TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study. J Transl Med 21:847. PubMed PMID:37996923
Bassett, E, Broadbent, J, Gill, D, Burgess, S, Mason, AM. 2023. Inconsistency in UK Biobank Event Definitions From Different Data Sources and Its Impact on Bias and Generalizability: A Case Study of Venous Thromboembolism. Am J Epidemiol :. PubMed PMID:37981722
Pérez-Jeldres, T, Magne, F, Ascui, G, Alvares, D, Orellana, M, Alvarez-Lobos, M, Hernandez-Rocha, C, Azocar, L, Aguilar, N, Espino, A, Estela, R, Escobar, S, Zazueta, A, Baez, P, Silva, V, De La Vega, A, Arriagada, E, Pavez-Ovalle, C, Díaz-Asencio, A, Travisany, D, Miquel, JF, Villablanca, EJ, Kronenberg, M, Bustamante, ML. 2023. Amerindian ancestry proportion as a risk factor for inflammatory bowel diseases: results from a Latin American Andean cohort. Front Med (Lausanne) 10:1258395. PubMed PMID:37964883
Paz, V, Dashti, HS, Burgess, S, Garfield, V. 2023. Selection of genetic instruments in Mendelian randomisation studies of sleep traits. Sleep Med 112:342-351. PubMed PMID:37956646
Zhou, F, Soremekun, O, Chikowore, T, Fatumo, S, Barroso, I, Morris, AP, Asimit, JL. 2023. Leveraging information between multiple population groups and traits improves fine-mapping resolution. Nat Commun 14:7279. PubMed PMID:37949886
Hernáez, Á, Lee, Y, Page, CM, Skåra, KH, Håberg, SE, Magnus, P, Njølstad, PR, Andreassen, OA, Corfield, EC, Havdahl, A, Fraser, A, Burgess, S, Lawlor, DA, Magnus, MC. 2023. Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study. Hum Reprod :. PubMed PMID:37949105
Kreuzaler, P, Inglese, P, Ghanate, A, Gjelaj, E, Wu, V, Panina, Y, Mendez-Lucas, A, MacLachlan, C, Patani, N, Hubert, CB, Huang, H, Greenidge, G, Rueda, OM, Taylor, AJ, Karali, E, Kazanc, E, Spicer, A, Dexter, A, Lin, W, Thompson, D, Silva Dos Santos, M, Calvani, E, Legrave, N, Ellis, JK, Greenwood, W, Green, M, Nye, E, Still, E, CRUK Rosetta Grand Challenge Consortium, Barry, S, Goodwin, RJA, Bruna, A, Caldas, C, MacRae, J, de Carvalho, LPS, Poulogiannis, G, McMahon, G, Takats, Z, Bunch, J, Yuneva, M. 2023. Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer. Nat Metab 5:1870-1886. PubMed PMID:37946084
Larsson, SC, Butterworth, AS, Burgess, S. 2023. Mendelian randomization for cardiovascular diseases: principles and applications. Eur Heart J :. PubMed PMID:37935836
Hall, VJ, Insalata, F, Foulkes, S, Kirwan, P, Sparkes, D, Atti, A, Cole, M, de Lacy, E, Price, L, Corrigan, D, Brown, CS, Islam, J, Charlett, A, Hopkins, S, SIREN Study Group. 2023. Effectiveness of BNT162b2 mRNA vaccine third doses and previous infection in protecting against SARS-CoV-2 infections during the Delta and Omicron variant waves; the UK SIREN cohort study September 2021 to February 2022. J Infect :. PubMed PMID:37926119
Chen, S, Marshall, T, Jackson, C, Cooper, J, Crowe, F, Nirantharakumar, K, Saunders, CL, Kirk, P, Richardson, S, Edwards, D, Griffin, S, Yau, C, Barrett, JK. 2023. Sociodemographic characteristics and longitudinal progression of multimorbidity: A multistate modelling analysis of a large primary care records dataset in England. PLoS Med 20:e1004310. PubMed PMID:37922316
Patel, A, Ye, T, Xue, H, Lin, Z, Xu, S, Woolf, B, Mason, AM, Burgess, S. 2023. MendelianRandomization v0.9.0: updates to an R package for performing Mendelian randomization analyses using summarized data. Wellcome Open Res 8:449. PubMed PMID:37915953
Geulayov, G, Casey, D, Bale, L, Brand, F, Clements, C, Kapur, N, Ness, J, Waters, K, White, S, Hawton, K. 2023. Variation in the clinical management of self-harm by area-level socio-economic deprivation: findings from the multicenter study of self-harm in England. Psychol Med :1-12. PubMed PMID:37905705
Yap, C, Solovyeva, O, de Bono, J, Rekowski, J, Patel, D, Jaki, T, Mander, A, Evans, TRJ, Peck, R, Hayward, KS, Hopewell, S, Ursino, M, Rantell, KR, Calvert, M, Lee, S, Kightley, A, Ashby, D, Chan, AW, Garrett-Mayer, E, Isaacs, JD, Golub, R, Kholmanskikh, O, Richards, D, Boix, O, Matcham, J, Seymour, L, Ivy, SP, Marshall, LV, Hommais, A, Liu, R, Tanaka, Y, Berlin, J, Espinasse, A, Dimairo, M, Weir, CJ. 2023. Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ 383:e076387. PubMed PMID:37863501
Yap, C, Rekowski, J, Ursino, M, Solovyeva, O, Patel, D, Dimairo, M, Weir, CJ, Chan, AW, Jaki, T, Mander, A, Evans, TRJ, Peck, R, Hayward, KS, Calvert, M, Rantell, KR, Lee, S, Kightley, A, Hopewell, S, Ashby, D, Garrett-Mayer, E, Isaacs, J, Golub, R, Kholmanskikh, O, Richards, DP, Boix, O, Matcham, J, Seymour, L, Ivy, SP, Marshall, LV, Hommais, A, Liu, R, Tanaka, Y, Berlin, J, Espinasse, A, de Bono, J. 2023. Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ 383:e076386. PubMed PMID:37863491
Li, W, Cornelius, V, Finfer, S, Venkatesh, B, Billot, L. 2023. Adaptive designs in critical care trials: a simulation study. BMC Med Res Methodol 23:236. PubMed PMID:37853343
Roychowdhury, T, Klarin, D, Levin, MG, Spin, JM, Rhee, YH, Deng, A, Headley, CA, Tsao, NL, Gellatly, C, Zuber, V, Shen, F, Hornsby, WE, Laursen, IH, Verma, SS, Locke, AE, Einarsson, G, Thorleifsson, G, Graham, SE, Dikilitas, O, Pattee, JW, Judy, RL, Pauls-Verges, F, Nielsen, JB, Wolford, BN, Brumpton, BM, Dilmé, J, Peypoch, O, Juscafresa, LC, Edwards, TL, Li, D, Banasik, K, Brunak, S, Jacobsen, RL, Garcia-Barrio, MT, Zhang, J, Rasmussen, LM, Lee, R, Handa, A, Wanhainen, A, Mani, K, Lindholt, JS, Obel, LM, Strauss, E, Oszkinis, G, Nelson, CP, Saxby, KL, van Herwaarden, JA, van der Laan, SW, van Setten, J, Camacho, M, Davis, FM, Wasikowski, R, Tsoi, LC, Gudjonsson, JE, Eliason, JL, Coleman, DM, Henke, PK, Ganesh, SK, Chen, YE, Guan, W, Pankow, JS, Pankratz, N, Pedersen, OB, Erikstrup, C, Tang, W, Hveem, K, Gudbjartsson, D, Gretarsdottir, S, Thorsteinsdottir, U, Holm, H, Stefansson, K, Ferreira, MA, Baras, A, Kullo, IJ, Ritchie, MD, Christensen, AH, Iversen, KK, Eldrup, N, Sillesen, H, Ostrowski, SR, Bundgaard, H, Ullum, H, Burgess, S, Gill, D, Gallagher, K, Sabater-Lleal, M, DiscovEHR, Regeneron Genetics Center, UK Aneurysm Growth Study, DBDS Genomic Consortium, VA Million Veteran Program, Surakka, I, Jones, GT, Bown, MJ, Tsao, PS, Willer, CJ, Damrauer, SM. 2023. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nat Genet 55:1831-1842. PubMed PMID:37845353
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