MRC Biostatistics UnitThe MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy
Our latest published papers can be viewed using the following link
Antoniou, M, Kolamunnage-Dona, R, Wason, J, Bathia, R, Billingham, C, Bliss, JM, Brown, LC, Gillman, A, Paul, J, Jorgensen, AL. 2019. Biomarker-guided trials: Challenges in practice. Contemp Clin Trials Commun 16:100493. PubMed PMID:31788574
Mazarello Paes, V, Barrett, JK, Dunger, DB, Gevers, EF, Taylor-Robinson, DC, Viner, RM, Stephenson, TJ. 2019. Factors predicting poor glycaemic control in the first two years of childhood onset type 1 diabetes in a cohort from East London, UK: Analyses using mixed effects fractional polynomial models. Pediatr Diabetes :. PubMed PMID:31782879
Allara, E, Morani, G, Carter, P, Gkatzionis, A, Zuber, V, Foley, CN, Rees, JM, Mason, AM, Bell, S, Gill, D, Lindstroem, S, Butterworth, AS, Di Angelantonio, E, Peters, J, Burgess, S. 2019. Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-angled Mendelian Randomization Investigation. Circ Genom Precis Med :. PubMed PMID:31756303
White, IR, Joseph, R, Best, N. 2019. A causal modelling framework for reference-based imputation and tipping point analysis in clinical trials with quantitative outcome. J Biopharm Stat :1-17. PubMed PMID:31718423
Williams, DM, Finan, C, Schmidt, AF, Burgess, S, Hingorani, AD. 2019. Lipid lowering and Alzheimer's disease risk: a Mendelian randomization study. Ann. Neurol. :. PubMed PMID:31714636
Nath, AP, Ritchie, SC, Grinberg, NF, Tang, HH, Huang, QQ, Teo, SM, Ahola-Olli, AV, Würtz, P, Havulinna, AS, Santalahti, K, Pitkänen, N, Lehtimäki, T, Kähönen, M, Lyytikäinen, LP, Raitoharju, E, Seppälä, I, Sarin, AP, Ripatti, S, Palotie, A, Perola, M, Viikari, JS, Jalkanen, S, Maksimow, M, Salmi, M, Wallace, C, Raitakari, OT, Salomaa, V, Abraham, G, Kettunen, J, Inouye, M. 2019. Multivariate Genome-Wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy. Am. J. Hum. Genet. :. PubMed PMID:31679650
Michiels, S, Wason, J. 2019. Overestimated treatment effects in randomised phase II trials: What's up doctor?. Eur. J. Cancer 123:116-117. PubMed PMID:31678769
Hampel, H, Vergallo, A, Afshar, M, Akman-Anderson, L, Arenas, J, Benda, N, Batrla, R, Broich, K, Caraci, F, Cuello, AC, Emanuele, E, Haberkamp, M, Kiddle, SJ, Lucía, A, Mapstone, M, Verdooner, SR, Woodcock, J, Lista, S. 2019. Blood-based systems biology biomarkers for next-generation clinical trials in Alzheimer's disease . Dialogues Clin Neurosci 21:177-191. PubMed PMID:31636492
Bahls, M, Lorenz, MW, Dörr, M, Gao, L, Kitagawa, K, Tuomainen, TP, Agewall, S, Berenson, G, Catapano, AL, Norata, GD, Bots, ML, van Gilst, W, Asselbergs, FW, Brouwers, FP, Uthoff, H, Sander, D, Poppert, H, Hecht Olsen, M, Empana, JP, Schminke, U, Baldassarre, D, Veglia, F, Franco, OH, Kavousi, M, de Groot, E, Mathiesen, EB, Grigore, L, Polak, JF, Rundek, T, Stehouwer, CD, Skilton, MR, Hatzitolios, AI, Savopoulos, C, Ntaios, G, Plichart, M, McLachlan, S, Lind, L, Willeit, P, Steinmetz, H, Desvarieux, M, Ikram, MA, Johnsen, SH, Schmidt, C, Willeit, J, Ducimetiere, P, Price, JF, Bergström, G, Kauhanen, J, Kiechl, S, Sitzer, M, Bickel, H, Sacco, RL, Hofman, A, Völzke, H, Thompson, SG, PROG-IMT Study Group. 2019. Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium. Eur J Prev Cardiol :2047487319877078. PubMed PMID:31619084
Barber, MRW, Hanly, JG, Su, L, Urowitz, MB, St Pierre, Y, Romero-Diaz, J, Gordon, C, Bae, SC, Bernatsky, S, Wallace, DJ, Merrill, JT, Isenberg, DA, Rahman, A, Ginzler, EM, Petri, M, Bruce, IN, Dooley, MA, Fortin, PR, Gladman, DD, Sanchez-Guerrero, J, Steinsson, K, Ramsey-Goldman, R, Khamashta, MA, Aranow, C, Mackay, M, Alarcón, GS, Manzi, S, Nived, O, Jönsen, A, Zoma, AA, van Vollenhoven, RF, Ramos-Casals, M, Ruiz-Irastorza, G, Lim, SS, Kalunian, KC, Inanc, M, Kamen, DL, Peschken, CA, Jacobsen, S, Askanase, A, Farewell, V, Stoll, T, Buyon, J, Clarke, AE. 2019. Economic evaluation of damage accrual in an international SLE inception cohort using a multi-state model approach. Arthritis Care Res (Hoboken) :. PubMed PMID:31609532
Strauss, ME, Kirk, PDW, Reid, JE, Wernisch, L. 2019. GPseudoClust: deconvolution of shared pseudo-profiles at single-cell resolution. Bioinformatics :. PubMed PMID:31608923
Bonnett, LJ, White, SR. 2019. Investigating populations via penguins and their poo!. Teach Stat 41:101-105. PubMed PMID:31588155
Seaman, S, Dukes, O, Keogh, R, Vansteelandt, S. 2019. Adjusting for time-varying confounders in survival analysis using structural nested cumulative survival time models. Biometrics :. PubMed PMID:31562652
Hickman, M, Dillon, JF, Elliott, L, De Angelis, D, Vickerman, P, Foster, G, Donnan, P, Eriksen, A, Flowers, P, Goldberg, D, Hollingworth, W, Ijaz, S, Liddell, D, Mandal, S, Martin, N, Beer, LJZ, Drysdale, K, Fraser, H, Glass, R, Graham, L, Gunson, RN, Hamilton, E, Harris, H, Harris, M, Harris, R, Heinsbroek, E, Hope, V, Horwood, J, Inglis, SK, Innes, H, Lane, A, Meadows, J, McAuley, A, Metcalfe, C, Migchelsen, S, Murray, A, Myring, G, Palmateer, NE, Presanis, A, Radley, A, Ramsay, M, Samartsidis, P, Simmons, R, Sinka, K, Vojt, G, Ward, Z, Whiteley, D, Yeung, A, Hutchinson, SJ. 2019. Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) - a natural experiment (protocol). BMJ Open 9:e029538. PubMed PMID:31551376
Pereira, DIA, Mohammed, NI, Ofordile, O, Camara, F, Baldeh, B, Mendy, T, Sanyang, C, Jallow, AT, Hossain, I, Wason, J, Prentice, AM. 2018. A novel nano-iron supplement to safely combat iron deficiency and anaemia in young children: The IHAT-GUT double-blind, randomised, placebo-controlled trial protocol. Gates Open Res 2:48. PubMed PMID:30569038
Rees, JMB, Wood, AM, Dudbridge, F, Burgess, S. 2019. Robust methods in Mendelian randomization via penalization of heterogeneous causal estimates. PLoS ONE 14:e0222362. PubMed PMID:31545794
Steyerberg, EW, Wiegers, E, Sewalt, C, Buki, A, Citerio, G, De Keyser, V, Ercole, A, Kunzmann, K, Lanyon, L, Lecky, F, Lingsma, H, Manley, G, Nelson, D, Peul, W, Stocchetti, N, von Steinbüchel, N, Vande Vyvere, T, Verheyden, J, Wilson, L, Maas, AIR, Menon, DK, CENTER-TBI Participants and Investigators. 2019. Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study. Lancet Neurol 18:923-934. PubMed PMID:31526754
Mourragui, S, Loog, M, van de Wiel, MA, Reinders, MJT, Wessels, LFA. 2019. PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors. Bioinformatics 35:i510-i519. PubMed PMID:31510654
Chen, H, Moreno-Moral, A, Pesce, F, Devapragash, N, Mancini, M, Heng, EL, Rotival, M, Srivastava, PK, Harmston, N, Shkura, K, Rackham, OJL, Yu, WP, Sun, XM, Tee, NGZ, Tan, ELS, Barton, PJR, Felkin, LE, Lara-Pezzi, E, Angelini, G, Beltrami, C, Pravenec, M, Schafer, S, Bottolo, L, Hubner, N, Emanueli, C, Cook, SA, Petretto, E. 2019. Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling. Nat Commun 10:4085. PubMed PMID:31501434
Bird, SM. 2019. Health in the UK. Lancet 394:827-828. PubMed PMID:31498093
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