The MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy

Our latest published papers can be viewed using the following link

Seaman, SR, Keogh, RH, Dukes, O, Vansteelandt, S. 2021. Using generalized linear models to implement g-estimation for survival data with time-varying confounding. Stat Med :. PubMed PMID:33942919

Ruffieux, H, Fairfax, BP, Nassiri, I, Vigorito, E, Wallace, C, Richardson, S, Bottolo, L. 2021. EPISPOT: An epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies. Am J Hum Genet :. PubMed PMID:33909991

Sobczyk, MK, Richardson, TG, Zuber, V, Min, JL, Gaunt, TR, Paternoster, L, eQTLGen Consortium, BIOS Consortium, GoDMC. 2021. Triangulating molecular evidence to prioritize candidate causal genes at established atopic dermatitis loci. J Invest Dermatol :. PubMed PMID:33901562

Kuś, A, Kjærgaard, AD, Marouli, E, Del Greco M, F, Sterenborg, RBTM, Chaker, L, Peeters, RP, Bednarczuk, T, Åsvold, BO, Burgess, S, Deloukas, P, Teumer, A, Ellervik, C, Medici, M. 2021. Thyroid function and mood disorders: a Mendelian Randomization study. Thyroid :. PubMed PMID:33899528

Laydon, DJ, Mishra, S, Hinsley, WR, Samartsidis, P, Flaxman, S, Gandy, A, Ferguson, NM, Bhatt, S. 2021. Modelling the impact of the tier system on SARS-CoV-2 transmission in the UK between the first and second national lockdowns. BMJ Open 11:e050346. PubMed PMID:33888533

Yuan, S, Mason, AM, Carter, P, Burgess, S, Larsson, SC. 2021. Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study. BMC Med 19:97. PubMed PMID:33888102

Pavlou, M, Qu, C, Omar, RZ, Seaman, SR, Steyerberg, EW, White, IR, Ambler, G. 2021. Estimation of required sample size for external validation of risk models for binary outcomes. Stat Methods Med Res :9622802211007522. PubMed PMID:33881369

Gaziano, L, Giambartolomei, C, Pereira, AC, Gaulton, A, Posner, DC, Swanson, SA, Ho, YL, Iyengar, SK, Kosik, NM, Vujkovic, M, Gagnon, DR, Bento, AP, Barrio-Hernandez, I, Rönnblom, L, Hagberg, N, Lundtoft, C, Langenberg, C, Pietzner, M, Valentine, D, Gustincich, S, Tartaglia, GG, Allara, E, Surendran, P, Burgess, S, Zhao, JH, Peters, JE, Prins, BP, Angelantonio, ED, Devineni, P, Shi, Y, Lynch, KE, DuVall, SL, Garcon, H, Thomann, LO, Zhou, JJ, Gorman, BR, Huffman, JE, O'Donnell, CJ, Tsao, PS, Beckham, JC, Pyarajan, S, Muralidhar, S, Huang, GD, Ramoni, R, Beltrao, P, Danesh, J, Hung, AM, Chang, KM, Sun, YV, Joseph, J, Leach, AR, Edwards, TL, Cho, K, Gaziano, JM, Butterworth, AS, Casas, JP, VA Million Veteran Program COVID-19 Science Initiative. 2021. Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19. Nat Med 27:668-676. PubMed PMID:33837377

Yuan, S, Carter, P, Vithayathil, M, Kar, S, Mason, AM, Burgess, S, Larsson, SC. 2021. Genetically predicted circulating B vitamins in relation to digestive system cancers. Br J Cancer :. PubMed PMID:33837300

Yuan, S, Burgess, S, Laffan, M, Mason, AM, Dichgans, M, Gill, D, Larsson, SC. 2021. Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study. J Am Heart Assoc 10:e019644. PubMed PMID:33834859

Larsson, SC, Lee, WH, Burgess, S, Allara, E. 2021. Plasma Cortisol and Risk of Atrial Fibrillation: A Mendelian Randomization Study. J Clin Endocrinol Metab :. PubMed PMID:33822969

Sinharay, R, Grant, AJ, Rivett, L, Blackwell, R, Mells, G, Gelson, W. 2021. Assessing efficacy of hepatocellular carcinoma prediction scores to prioritise hepatitis B surveillance in the COVID-19 era. GastroHep 3:80-87. PubMed PMID:33821150

Yee, CS, Gordon, C, Isenberg, DA, Griffiths, B, Teh, LS, Bruce, IN, Ahmad, Y, Rahman, A, Prabu, A, Akil, M, McHugh, N, Edwards, CJ, D'Cruz, D, Khamashta, MA, Farewell, VT. 2021. Comparison of responsiveness of BILAG-2004, SLEDAI-2000 and BILAG Systems Tally (BST). Arthritis Care Res (Hoboken) :. PubMed PMID:33787088

Ó Breasail, M, Ward, KA, Schoenbuchner, SM, Ceesay, M, Mendy, M, Jarjou, LM, Moore, SE, Prentice, A. 2021. Pregnancy-Related Change in pQCT and Bone Biochemistry in a Population With a Habitually Low Calcium Intake. J Bone Miner Res :. PubMed PMID:33784438

Collins, J, Astle, WJ, Megy, K, Mumford, AD, Vuckovic, D. 2021. Advances in understanding the pathogenesis of hereditary macrothrombocytopenia. Br J Haematol :. PubMed PMID:33783834

Fatumo, S, Chikowore, T, Kalyesubula, R, Nsubuga, RN, Asiki, G, Nashiru, O, Seeley, J, Crampin, AC, Nitsch, D, Smeeth, L, Kaleebu, P, Burgess, S, Nyirenda, M, Franceschini, N, Morris, AP, Tomlinson, L, Newton, R. 2021. Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Hum Mol Genet :. PubMed PMID:33783510

Treasure, T, Farewell, V, Macbeth, F, Batchelor, T, Milosevic, M, King, J, Zheng, Y, Leonard, P, Williams, NR, Brew-Graves, C, Fallowfield, L, PulMiCC investigators. 2021. Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) Cohort Study: analysis of case selection, risk factors and survival in a prospective observational study of 512 patients. Colorectal Dis :. PubMed PMID:33783109

Ballarini, NM, Burnett, T, Jaki, T, Jennison, C, König, F, Posch, M. 2021. Optimizing subgroup selection in two-stage adaptive enrichment and umbrella designs. Stat Med :. PubMed PMID:33783020

Ouma, LO, Grayling, MJ, Zheng, H, Wason, J. 2021. Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: A comparison of methods. Pharm Stat :. PubMed PMID:33759353

Warrier, V, Kwong, ASF, Luo, M, Dalvie, S, Croft, J, Sallis, HM, Baldwin, J, Munafò, MR, Nievergelt, CM, Grant, AJ, Burgess, S, Moore, TM, Barzilay, R, McIntosh, A, van IJzendoorn, MH, Cecil, CAM. 2021. Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach. Lancet Psychiatry 8:373-386. PubMed PMID:33740410

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Additional Material

We also have a repository of Reports, Published Material, Pre-prints and Technical Reports in our Additional Material webpage.