The MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy

Our latest published papers can be viewed using the following link

Jackson, CH. 2023. survextrap: a package for flexible and transparent survival extrapolation. BMC Med Res Methodol 23:282. PubMed PMID:38030986

Yuan, S, Xu, F, Zhang, H, Chen, J, Ruan, X, Li, Y, Burgess, S, Åkesson, A, Li, X, Gill, D, Larsson, SC. 2023. Proteomic insights into modifiable risk of venous thromboembolism and cardiovascular comorbidities. J Thromb Haemost :. PubMed PMID:38029854

Fagbamigbe, AF, Agrawal, U, Azcoaga-Lorenzo, A, MacKerron, B, Özyiğit, EB, Alexander, DC, Akbari, A, Owen, RK, Lyons, J, Lyons, RA, Denaxas, S, Kirk, P, Miller, AC, Harper, G, Dezateux, C, Brookes, A, Richardson, S, Nirantharakumar, K, Guthrie, B, Hughes, L, Kadam, UT, Khunti, K, Abrams, KR, McCowan, C. 2023. Clustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland. PLoS One 18:e0294666. PubMed PMID:38019832

Bird, SM. 2023. Opioid-related deaths and their counterpart by occurrence-era, age-group and co-implicated drugs: Scotland versus England and Wales. Br J Clin Pharmacol :. PubMed PMID:38009544

Rajasundaram, S, Zebardast, N, Mehta, P, Khawaja, AP, Warwick, A, Duchinski, K, Burgess, S, Gill, D, Segrè, AV, Wiggs, J. 2023. TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study. J Transl Med 21:847. PubMed PMID:37996923

Bassett, E, Broadbent, J, Gill, D, Burgess, S, Mason, AM. 2023. Inconsistency in UK Biobank Event Definitions From Different Data Sources and Its Impact on Bias and Generalizability: A Case Study of Venous Thromboembolism. Am J Epidemiol :. PubMed PMID:37981722

Pérez-Jeldres, T, Magne, F, Ascui, G, Alvares, D, Orellana, M, Alvarez-Lobos, M, Hernandez-Rocha, C, Azocar, L, Aguilar, N, Espino, A, Estela, R, Escobar, S, Zazueta, A, Baez, P, Silva, V, De La Vega, A, Arriagada, E, Pavez-Ovalle, C, Díaz-Asencio, A, Travisany, D, Miquel, JF, Villablanca, EJ, Kronenberg, M, Bustamante, ML. 2023. Amerindian ancestry proportion as a risk factor for inflammatory bowel diseases: results from a Latin American Andean cohort. Front Med (Lausanne) 10:1258395. PubMed PMID:37964883

Paz, V, Dashti, HS, Burgess, S, Garfield, V. 2023. Selection of genetic instruments in Mendelian randomisation studies of sleep traits. Sleep Med 112:342-351. PubMed PMID:37956646

Zhou, F, Soremekun, O, Chikowore, T, Fatumo, S, Barroso, I, Morris, AP, Asimit, JL. 2023. Leveraging information between multiple population groups and traits improves fine-mapping resolution. Nat Commun 14:7279. PubMed PMID:37949886

Hernáez, Á, Lee, Y, Page, CM, Skåra, KH, Håberg, SE, Magnus, P, Njølstad, PR, Andreassen, OA, Corfield, EC, Havdahl, A, Fraser, A, Burgess, S, Lawlor, DA, Magnus, MC. 2023. Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study. Hum Reprod :. PubMed PMID:37949105

Kreuzaler, P, Inglese, P, Ghanate, A, Gjelaj, E, Wu, V, Panina, Y, Mendez-Lucas, A, MacLachlan, C, Patani, N, Hubert, CB, Huang, H, Greenidge, G, Rueda, OM, Taylor, AJ, Karali, E, Kazanc, E, Spicer, A, Dexter, A, Lin, W, Thompson, D, Silva Dos Santos, M, Calvani, E, Legrave, N, Ellis, JK, Greenwood, W, Green, M, Nye, E, Still, E, CRUK Rosetta Grand Challenge Consortium, Barry, S, Goodwin, RJA, Bruna, A, Caldas, C, MacRae, J, de Carvalho, LPS, Poulogiannis, G, McMahon, G, Takats, Z, Bunch, J, Yuneva, M. 2023. Vitamin B₅ supports MYC oncogenic metabolism and tumor progression in breast cancer. Nat Metab 5:1870-1886. PubMed PMID:37946084

Larsson, SC, Butterworth, AS, Burgess, S. 2023. Mendelian randomization for cardiovascular diseases: principles and applications. Eur Heart J :. PubMed PMID:37935836

Hall, VJ, Insalata, F, Foulkes, S, Kirwan, P, Sparkes, D, Atti, A, Cole, M, de Lacy, E, Price, L, Corrigan, D, Brown, CS, Islam, J, Charlett, A, Hopkins, S, SIREN Study Group. 2023. Effectiveness of BNT162b2 mRNA vaccine third doses and previous infection in protecting against SARS-CoV-2 infections during the Delta and Omicron variant waves; the UK SIREN cohort study September 2021 to February 2022. J Infect :. PubMed PMID:37926119

Chen, S, Marshall, T, Jackson, C, Cooper, J, Crowe, F, Nirantharakumar, K, Saunders, CL, Kirk, P, Richardson, S, Edwards, D, Griffin, S, Yau, C, Barrett, JK. 2023. Sociodemographic characteristics and longitudinal progression of multimorbidity: A multistate modelling analysis of a large primary care records dataset in England. PLoS Med 20:e1004310. PubMed PMID:37922316

Patel, A, Ye, T, Xue, H, Lin, Z, Xu, S, Woolf, B, Mason, AM, Burgess, S. 2023. MendelianRandomization v0.9.0: updates to an R package for performing Mendelian randomization analyses using summarized data. Wellcome Open Res 8:449. PubMed PMID:37915953

Geulayov, G, Casey, D, Bale, L, Brand, F, Clements, C, Kapur, N, Ness, J, Waters, K, White, S, Hawton, K. 2023. Variation in the clinical management of self-harm by area-level socio-economic deprivation: findings from the multicenter study of self-harm in England. Psychol Med :1-12. PubMed PMID:37905705

Yap, C, Solovyeva, O, de Bono, J, Rekowski, J, Patel, D, Jaki, T, Mander, A, Evans, TRJ, Peck, R, Hayward, KS, Hopewell, S, Ursino, M, Rantell, KR, Calvert, M, Lee, S, Kightley, A, Ashby, D, Chan, AW, Garrett-Mayer, E, Isaacs, JD, Golub, R, Kholmanskikh, O, Richards, D, Boix, O, Matcham, J, Seymour, L, Ivy, SP, Marshall, LV, Hommais, A, Liu, R, Tanaka, Y, Berlin, J, Espinasse, A, Dimairo, M, Weir, CJ. 2023. Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ 383:e076387. PubMed PMID:37863501

Yap, C, Rekowski, J, Ursino, M, Solovyeva, O, Patel, D, Dimairo, M, Weir, CJ, Chan, AW, Jaki, T, Mander, A, Evans, TRJ, Peck, R, Hayward, KS, Calvert, M, Rantell, KR, Lee, S, Kightley, A, Hopewell, S, Ashby, D, Garrett-Mayer, E, Isaacs, J, Golub, R, Kholmanskikh, O, Richards, DP, Boix, O, Matcham, J, Seymour, L, Ivy, SP, Marshall, LV, Hommais, A, Liu, R, Tanaka, Y, Berlin, J, Espinasse, A, de Bono, J. 2023. Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ 383:e076386. PubMed PMID:37863491

Li, W, Cornelius, V, Finfer, S, Venkatesh, B, Billot, L. 2023. Adaptive designs in critical care trials: a simulation study. BMC Med Res Methodol 23:236. PubMed PMID:37853343

Roychowdhury, T, Klarin, D, Levin, MG, Spin, JM, Rhee, YH, Deng, A, Headley, CA, Tsao, NL, Gellatly, C, Zuber, V, Shen, F, Hornsby, WE, Laursen, IH, Verma, SS, Locke, AE, Einarsson, G, Thorleifsson, G, Graham, SE, Dikilitas, O, Pattee, JW, Judy, RL, Pauls-Verges, F, Nielsen, JB, Wolford, BN, Brumpton, BM, Dilmé, J, Peypoch, O, Juscafresa, LC, Edwards, TL, Li, D, Banasik, K, Brunak, S, Jacobsen, RL, Garcia-Barrio, MT, Zhang, J, Rasmussen, LM, Lee, R, Handa, A, Wanhainen, A, Mani, K, Lindholt, JS, Obel, LM, Strauss, E, Oszkinis, G, Nelson, CP, Saxby, KL, van Herwaarden, JA, van der Laan, SW, van Setten, J, Camacho, M, Davis, FM, Wasikowski, R, Tsoi, LC, Gudjonsson, JE, Eliason, JL, Coleman, DM, Henke, PK, Ganesh, SK, Chen, YE, Guan, W, Pankow, JS, Pankratz, N, Pedersen, OB, Erikstrup, C, Tang, W, Hveem, K, Gudbjartsson, D, Gretarsdottir, S, Thorsteinsdottir, U, Holm, H, Stefansson, K, Ferreira, MA, Baras, A, Kullo, IJ, Ritchie, MD, Christensen, AH, Iversen, KK, Eldrup, N, Sillesen, H, Ostrowski, SR, Bundgaard, H, Ullum, H, Burgess, S, Gill, D, Gallagher, K, Sabater-Lleal, M, DiscovEHR, Regeneron Genetics Center, UK Aneurysm Growth Study, DBDS Genomic Consortium, VA Million Veteran Program, Surakka, I, Jones, GT, Bown, MJ, Tsao, PS, Willer, CJ, Damrauer, SM. 2023. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nat Genet 55:1831-1842. PubMed PMID:37845353

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