Published Research

The MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy

Our latest published papers can be viewed using the following link

Kamat, MA, Blackshaw, JA, Young, R, Surendran, P, Burgess, S, Danesh, J, Butterworth, AS, Staley, JR. 2019. PhenoScanner V2: an expanded tool for searching human genotype-phenotype associations. Bioinformatics :. PubMed PMID:31233103

Brown, RB, Traylor, M, Burgess, S, Sawcer, S, Markus, HS. 2019. Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?. Stroke :STROKEAHA118023649. PubMed PMID:31221055

Grayling, MJ, Dimairo, M, Mander, AP, Jaki, TF. 2019. A review of perspectives on the use of randomization in phase II oncology trials. J. Natl. Cancer Inst. :. PubMed PMID:31218346

Whittaker, HR, Müllerova, H, Jarvis, D, Barnes, NC, Jones, PW, Compton, CH, Kiddle, SJ, Quint, JK. 2019. Inhaled corticosteroids, blood eosinophils, and FEV₁ decline in patients with COPD in a large UK primary health care setting. Int J Chron Obstruct Pulmon Dis 14:1063-1073. PubMed PMID:31213788

Larsson, SC, Bäck, M, Rees, JMB, Mason, AM, Burgess, S. 2019. Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study. Eur. Heart J. :. PubMed PMID:31195408

Parmar, MKB, Strang, J, Choo, L, Meade, AM, Bird, SM. 2019. Clarification re naloxone administered to study subject versus other overdose victim in the N-ALIVE pilot randomized trial. Addiction 114:1325. PubMed PMID:31161681

Allen, O, Jadkauskaite, L, Shafi, NT, Jackson, A, Athithan, V, Chiu, YD, Ies, E, Floto, RA, Haworth, CS. 2019. Microbiological evaluation of UV disinfection effectiveness in a specialist cystic fibrosis clinic. J. Cyst. Fibros. 18:e37-e39. PubMed PMID:31153817

Carter, AR, Gill, D, Davies, NM, Taylor, AE, Tillmann, T, Vaucher, J, Wootton, RE, Munafò, MR, Hemani, G, Malik, R, Seshadri, S, Woo, D, Burgess, S, Davey Smith, G, Holmes, MV, Tzoulaki, I, Howe, LD, Dehghan, A. 2019. Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study. BMJ 365:l1855. PubMed PMID:31122926

Crook, OM, Breckels, LM, Lilley, KS, Kirk, PDW, Gatto, L. 2019. A Bioconductor workflow for the Bayesian analysis of spatial proteomics. F1000Res 8:446. PubMed PMID:31119032

Lee, KM, Wason, J, Stallard, N. 2019. To add or not to add a new treatment arm to a multiarm study: A decision-theoretic framework. Stat Med :. PubMed PMID:31115078

Shigaki, D, Adato, O, Adhikari, AN, Dong, S, Hawkins-Hooker, A, Inoue, F, Juven-Gershon, T, Kenlay, H, Martin, B, Patra, A, Penzar, DD, Schubach, M, Xiong, C, Yan, Z, Boyle, AP, Kreimer, A, Kulakovskiy, IV, Reid, J, Unger, R, Yosef, N, Shendure, J, Ahituv, N, Kircher, M, Beer, MA. 2019. Integration of multiple epigenomic marks improves prediction of variant impact in saturation mutagenesis reporter assay. Hum. Mutat. :. PubMed PMID:31106481

Zwakenberg, SR, Burgess, S, Sluijs, I, Weiderpass, E, Beulens, JWJ, van der Schouw, YT. 2019. Circulating phylloquinone, inactive Matrix Gla protein and coronary heart disease risk: A two-sample Mendelian Randomization study. Clin Nutr :. PubMed PMID:31103344

Coles, AJ, Azzopardi, L, Kousin-Ezewu, O, Mullay, HK, Thompson, SA, Jarvis, L, Davies, J, Howlett, S, Rainbow, D, Babar, J, Sadler, TJ, Brown, JWL, Needham, E, May, K, Georgieva, ZG, Handel, AE, Maio, S, Deadman, M, Rota, I, Holländer, G, Dawson, S, Jayne, D, Seggewiss-Bernhardt, R, Douek, DC, Isaacs, JD, Jones, JL. 2019. Keratinocyte growth factor impairs human thymic recovery from lymphopenia. JCI Insight 5:. PubMed PMID:31063156

Price, MJ, Blake, H, Kenyon, S, White, IR, Jackson, D, Kirkham, JJ, Neilson, J, Deeks, JJ, Riley, RD. 2019. Empirical comparison of univariate and multivariate meta-analysis in Cochrane Pregnancy and Childbirth reviews with multiple binary outcomes. Res Synth Methods :. PubMed PMID:31058440

Bornschein, J, Wernisch, L, Secrier, M, Miremadi, A, Perner, J, MacRae, S, O'Donovan, M, Newton, R, Menon, S, Bower, L, Eldridge, MD, Devonshire, G, Cheah, C, Turkington, R, Hardwick, RH, Selgrad, M, Venerito, M, Malfertheiner, P, OCCAMS Consortium, Fitzgerald, RC. 2019. Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction. Int. J. Cancer :. PubMed PMID:31050820

Ochoa, E, Zuber, V, Fernandez-Jimenez, N, Bilbao, JR, Clark, GR, Maher, ER, Bottolo, L. 2019. MethylCal: Bayesian calibration of methylation levels. Nucleic Acids Res. :. PubMed PMID:31049595

Leday, GGR, Richardson, S. 2019. Fast Bayesian inference in large Gaussian graphical models. Biometrics :. PubMed PMID:31009060

Lee, KM, Wason, J. 2019. Design of experiments for a confirmatory trial of precision medicine. J Stat Plan Inference 199:179-187. PubMed PMID:31007363

di Pietro, M, Bertani, H, OʼDonovan, M, Santos, P, Alastal, H, Phillips, R, Ortiz-Fernández-Sordo, J, Iacucci, M, Modolell, I, Reggiani Bonetti, L, Ragunath, K, Wernisch, L. 2019. Development and Validation of Confocal Endomicroscopy Diagnostic Criteria for Low-Grade Dysplasia in Barrett's Esophagus. Clin Transl Gastroenterol 10:e00014. PubMed PMID:30985335

Edlmann, E, Thelin, EP, Caldwell, K, Turner, C, Whitfield, P, Bulters, D, Holton, P, Suttner, N, Owusu-Agyemang, K, Al-Tamimi, YZ, Gatt, D, Thomson, S, Anderson, IA, Richards, O, Gherle, M, Toman, E, Nandi, D, Kane, P, Pantaleo, B, Davis-Wilkie, C, Tarantino, S, Barton, G, Marcus, HJ, Chari, A, Belli, A, Bond, S, Gafoor, R, Dawson, S, Whitehead, L, Brennan, P, Wilkinson, I, Kolias, AG, Hutchinson, PJA, Dex-CSDH trial collaborative and BNTRC collaborative.. 2019. Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase. Sci Rep 9:5885. PubMed PMID:30971773

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Additional Material

We also have a repository of Reports, Published Material, Pre-prints and Technical Reports in our Additional Material webpage.