The MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy

Our latest published papers can be viewed using the following link

Barnett, HY, Villar, SS, Geys, H, Jaki, T. 2021. A novel statistical test for treatment differences in clinical trials using a response adaptive forward looking gittins index rule. Biometrics :. PubMed PMID:34669968

Zheng, J, Zhang, Y, Rasheed, H, Walker, V, Sugawara, Y, Li, J, Leng, Y, Elsworth, B, Wootton, RE, Fang, S, Yang, Q, Burgess, S, Haycock, PC, Borges, MC, Cho, Y, Carnegie, R, Howell, A, Robinson, J, Thomas, LF, Brumpton, BM, Hveem, K, Hallan, S, Franceschini, N, Morris, AP, Köttgen, A, Pattaro, C, Wuttke, M, Yamamoto, M, Kashihara, N, Akiyama, M, Kanai, M, Matsuda, K, Kamatani, Y, Okada, Y, Walters, R, Millwood, IY, Chen, Z, Davey Smith, G, Barbour, S, Yu, C, Åsvold, BO, Zhang, H, Gaunt, TR. 2021. Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. Int J Epidemiol :. PubMed PMID:34669934

Hutchinson, A, Reales, G, Willis, T, Wallace, C. 2021. Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR. PLoS Genet 17:e1009853. PubMed PMID:34669738

Hernáez, Á, Rogne, T, Skåra, KH, Håberg, SE, Page, CM, Fraser, A, Burgess, S, Lawlor, DA, Magnus, MC. 2021. Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study. Hum Reprod :. PubMed PMID:34668019

Jugnarain, DV, Halford, R, Smith, S, Hickman, M, Samartsidis, P, Foster, GR. 2021. Role of peer support in a hepatitis C elimination program. J Viral Hepat :. PubMed PMID:34664352

Wall, C, Huang, Y, Le, EPV, Ćorović, A, Uy, CP, Gopalan, D, Ma, C, Manavaki, R, Fryer, TD, Aloj, L, Graves, MJ, Tombetti, E, Ariff, B, Bambrough, P, Hoole, SP, Rusk, RA, Jayne, DR, Dweck, MR, Newby, D, Fayad, ZA, Bennett, MR, Peters, JE, Slomka, P, Dey, D, Mason, JC, Rudd, JHF, Tarkin, JM. 2021. Pericoronary and periaortic adipose tissue density are associated with inflammatory disease activity in Takayasu arteritis and atherosclerosis. Eur Heart J Open 1:oeab019. PubMed PMID:34661196

Lingjærde, C, Lien, TG, Borgan, Ø, Bergholtz, H, Glad, IK. 2021. Tailored graphical lasso for data integration in gene network reconstruction. BMC Bioinformatics 22:498. PubMed PMID:34654363

de Vlaming, R, Slob, EAW, Jansen, PR, Dagher, A, Koellinger, PD, Groenen, PJF, Rietveld, CA. 2021. Multivariate analysis reveals shared genetic architecture of brain morphology and human behavior. Commun Biol 4:1180. PubMed PMID:34642422

Woitek, R, McLean, MA, Ursprung, S, Rueda, OM, Manzano Garcia, R, Locke, MJ, Beer, L, Baxter, G, Rundo, L, Provenzano, E, Kaggie, JD, Patterson, A, Frary, A, Field-Rayner, J, Papalouka, V, Kane, J, Benjamin, AJV, Gill, AB, Priest, AN, Lewis, DY, Russell, R, Grimmer, A, White, B, Latimer, EC, Patterson, I, Schiller, A, Carmo, B, Slough, R, Lanz, T, Wason, J, Schulte, RF, Chin, SF, Graves, MJ, Gilbert, FJ, Abraham, J, Caldas, C, Brindle, KM, Sala, E, Gallagher, FA. 2021. Hyperpolarized carbon-13 MRI for early response assessment of neoadjuvant chemotherapy in breast cancer patients. Cancer Res :. PubMed PMID:34625424

Fazel, M, Puntis, S, White, SR, Townsend, A, Mansfield, KL, Viner, R, Herring, J, Pollard, AJ, Freeman, D. 2021. Willingness of children and adolescents to have a COVID-19 vaccination: Results of a large whole schools survey in England. EClinicalMedicine :101144. PubMed PMID:34608453

Larsson, SC, Kar, S, Perry, JRB, Carter, P, Vithayathil, M, Mason, AM, Easton, DF, Burgess, S. 2021. Serum Estradiol and 20 Site-Specific Cancers in Women: Mendelian Randomization Study. J Clin Endocrinol Metab :. PubMed PMID:34601599

Mulvey, CM, Breckels, LM, Crook, OM, Sanders, DJ, Ribeiro, ALR, Geladaki, A, Christoforou, A, Britovšek, NK, Hurrell, T, Deery, MJ, Gatto, L, Smith, AM, Lilley, KS. 2021. Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line. Nat Commun 12:5773. PubMed PMID:34599159

Watson, RA, Tong, O, Cooper, R, Taylor, CA, Sharma, PK, de Los Aires, AV, Mahé, EA, Ruffieux, H, Nassiri, I, Middleton, MR, Fairfax, BP. 2021. Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8⁺ T cell clone size and cytotoxicity. Sci Immunol 6:eabj8825. PubMed PMID:34597125

Wallace, C. 2021. A more accurate method for colocalisation analysis allowing for multiple causal variants. PLoS Genet 17:e1009440. PubMed PMID:34587156

Álvarez-Esteban, PC, Del Barrio, E, Rueda, OM, Rueda, C. 2021. Predicting COVID-19 progression from diagnosis to recovery or death linking primary care and hospital records in Castilla y León (Spain). PLoS One 16:e0257613. PubMed PMID:34543345

Simons, PIHG, Cornelissen, MEB, Valkenburg, O, Onland-Moret, NC, van der Schouw, YT, Stehouwer, CDA, Burgess, S, Brouwers, MCGJ. 2021. Causal relationship between polycystic ovary syndrome and coronary artery disease: A Mendelian randomisation study. Clin Endocrinol (Oxf) :. PubMed PMID:34524719

Whittaker, HR, Kiddle, SJ, Quint, JK. 2021. Challenges and Pitfalls of Using Repeat Spirometry Recordings in Routine Primary Care Data to Measure FEV₁ Decline in a COPD Population. Pragmat Obs Res 12:119-130. PubMed PMID:34512071

Culeddu, G, Su, L, Cheng, Y, Pereira, DIA, Payne, RA, Powell, JJ, Hughes, DA. 2021. Novel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?. Br J Clin Pharmacol :. PubMed PMID:34510516

Egle, M, Hilal, S, Tuladhar, AM, Pirpamer, L, Hofer, E, Duering, M, Wason, J, Morris, RG, Dichgans, M, Schmidt, R, Tozer, D, Chen, C, de Leeuw, FE, Markus, HS. 2021. Prediction of dementia using diffusion tensor MRI measures: the OPTIMAL collaboration. J Neurol Neurosurg Psychiatry :. PubMed PMID:34509999

Ye, Z, Kappelmann, N, Moser, S, Davey Smith, G, Burgess, S, Jones, PB, Khandaker, GM. 2021. Role of inflammation in depression and anxiety: Tests for disorder specificity, linearity and potential causality of association in the UK Biobank. EClinicalMedicine 38:100992. PubMed PMID:34505025

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Additional Material

We also have a repository of Reports, Published Material, Pre-prints and Technical Reports in our Additional Material webpage.