Published Research

The MRC Biostatistics Unit keeps a record of all known BSU publications in line with the MRC’s Open Access Policy

Our latest published papers can be viewed using the following link

Abbas, R, Rossoni, C, Jaki, T, Paoletti, X, Mozgunov, P. 2020. A comparison of phase I dose-finding designs in clinical trials with monotonicity assumption violation. Clin Trials :1740774520932130. PubMed PMID:32631095

Cabassi, A, Kirk, PDW. 2020. Multiple kernel learning for integrative consensus clustering of 'omic datasets. Bioinformatics :. PubMed PMID:32592464

Turro, E, Astle, WJ, Megy, K, Gräf, S, Greene, D, Shamardina, O, Allen, HL, Sanchis-Juan, A, Frontini, M, Thys, C, Stephens, J, Mapeta, R, Burren, OS, Downes, K, Haimel, M, Tuna, S, Deevi, SVV, Aitman, TJ, Bennett, DL, Calleja, P, Carss, K, Caulfield, MJ, Chinnery, PF, Dixon, PH, Gale, DP, James, R, Koziell, A, Laffan, MA, Levine, AP, Maher, ER, Markus, HS, Morales, J, Morrell, NW, Mumford, AD, Ormondroyd, E, Rankin, S, Rendon, A, Richardson, S, Roberts, I, Roy, NBA, Saleem, MA, Smith, KGC, Stark, H, Tan, RYY, Themistocleous, AC, Thrasher, AJ, Watkins, H, Webster, AR, Wilkins, MR, Williamson, C, Whitworth, J, Humphray, S, Bentley, DR, NIHR BioResource for the 100,000 Genomes Project, Kingston, N, Walker, N, Bradley, JR, Ashford, S, Penkett, CJ, Freson, K, Stirrups, KE, Raymond, FL, Ouwehand, WH. 2020. Whole-genome sequencing of patients with rare diseases in a national health system. Nature 583:96-102. PubMed PMID:32581362

Lee, KM, Wason, J. 2020. Including non-concurrent control patients in the analysis of platform trials: is it worth it?. BMC Med Res Methodol 20:165. PubMed PMID:32580702

Pirani, M, Mason, AJ, Hansell, AL, Richardson, S, Blangiardo, M. 2020. A flexible hierarchical framework for improving inference in area-referenced environmental health studies. Biom J :. PubMed PMID:32567714

Robertson, DS, Wason, JMS, Bretz, F. 2020. Graphical approaches for the control of generalized error rates. Stat Med :. PubMed PMID:32557848

Mesa-Eguiagaray, I, Wild, SH, Rosenberg, PS, Bird, SM, Brewster, DH, Hall, PS, Cameron, DA, Morrison, D, Figueroa, JD. 2020. Distinct temporal trends in breast cancer incidence from 1997 to 2016 by molecular subtypes: a population-based study of Scottish cancer registry data. Br. J. Cancer :. PubMed PMID:32555534

Dimairo, M, Pallmann, P, Wason, J, Todd, S, Jaki, T, Julious, SA, Mander, AP, Weir, CJ, Koenig, F, Walton, MK, Nicholl, JP, Coates, E, Biggs, K, Hamasaki, T, Proschan, MA, Scott, JA, Ando, Y, Hind, D, Altman, DG, ACE Consensus Group. 2020. The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. BMJ 369:m115. PubMed PMID:32554564

Larsson, SC, Michaëlsson, K, Burgess, S. 2020. IGF-1 and cardiometabolic diseases: a Mendelian randomisation study. Diabetologia :. PubMed PMID:32548700

Roxburgh, R, Willoughby, E, Seaman, S. Regarding the publication The Multiple Sclerosis Severity Score: Fluctuations and prognostic ability in a longitudinal cohort of patients with MS authored by RH Gross et al. Mult Scler J Exp Transl Clin 6:2055217320927421. PubMed PMID:32547777

Dimairo, M, Pallmann, P, Wason, J, Todd, S, Jaki, T, Julious, SA, Mander, AP, Weir, CJ, Koenig, F, Walton, MK, Nicholl, JP, Coates, E, Biggs, K, Hamasaki, T, Proschan, MA, Scott, JA, Ando, Y, Hind, D, Altman, DG, ACE Consensus Group. 2020. The adaptive designs CONSORT extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. Trials 21:528. PubMed PMID:32546273

Willeit, P, Tschiderer, L, Allara, E, Reuber, K, Seekircher, L, Gao, L, Liao, X, Lonn, E, Gerstein, HC, Yusuf, S, Brouwers, FP, Asselbergs, FW, van Gilst, W, Anderssen, SA, Grobbee, DE, Kastelein, JJP, Visseren, FLJ, Ntaios, G, Hatzitolios, AI, Savopoulos, C, Nieuwkerk, PT, Stroes, E, Walters, M, Higgins, P, Dawson, J, Gresele, P, Guglielmini, G, Migliacci, R, Ezhov, M, Safarova, M, Balakhonova, T, Sato, E, Amaha, M, Nakamura, T, Kapellas, K, Jamieson, LM, Skilton, M, Blumenthal, JA, Hinderliter, A, Sherwood, A, Smith, PJ, van Agtmael, MA, Reiss, P, van Vonderen, MGA, Kiechl, S, Klingenschmid, G, Sitzer, M, Stehouwer, CDA, Uthoff, H, Zou, ZY, Cunha, AR, Neves, MF, Witham, MD, Park, HW, Lee, MS, Bae, JH, Bernal, E, Wachtell, K, Kjeldsen, SE, Olsen, MH, Preiss, D, Sattar, N, Beishuizen, E, Huisman, MV, Espeland, MA, Schmidt, C, Agewall, S, Ok, E, Aşçi, G, de Groot, E, Grooteman, MPC, Blankestijn, PJ, Bots, ML, Sweeting, MJ, Thompson, SG, Lorenz, MW, PROG-IMT and the Proof-ATHERO Study Groups. 2020. Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100,667 Patients. Circulation :. PubMed PMID:32546049

Kunst, N, Wilson, ECF, Glynn, D, Alarid-Escudero, F, Baio, G, Brennan, A, Fairley, M, Goldhaber-Fiebert, JD, Jackson, C, Jalal, H, Menzies, NA, Strong, M, Thom, H, Heath, A, Collaborative Network for Value of Information. 2020. Computing the Expected Value of Sample Information Efficiently: Practical Guidance and Recommendations for Four Model-Based Methods. Value Health 23:734-742. PubMed PMID:32540231

Gasperoni, F, Ieva, F, Paganoni, AM, Jackson, CH, Sharples, L. 2020. Evaluating the effect of healthcare providers on the clinical path of heart failure patients through a semi-Markov, multi-state model. BMC Health Serv Res 20:533. PubMed PMID:32532254

Gao, L, Robertson, JR, Bird, SM. 2020. Scotland's 2009-2015 methadone-prescription cohort: quintiles for daily-dose of prescribed methadone and risk of methadone-specific death. Br J Clin Pharmacol :. PubMed PMID:32530053

Urowitz, MB, Gladman, DD, Farewell, V, Su, J, Romero-Diaz, J, Bae, SC, Fortin, PR, Sanchez-Guerrero, J, Clarke, AE, Bernatsky, S, Gordon, C, Hanly, JG, Wallace, DJ, Isenberg, D, Rahman, A, Merrill, J, Ginzler, E, Alarcón, GS, Chatham, WW, Petri, M, Bruce, IN, Khamashta, M, Aranow, C, Dooley, M, Manzi, S, Ramsey-Goldman, R, Nived, O, Jönsen, A, Steinsson, K, Zoma, A, Ruiz-Irastorza, G, Lim, S, Kalunian, KC, Ỉnanç, M, van Vollenhoven, R, Ramos-Casals, M, Kamen, DL, Jacobsen, S, Peschken, C, Askanase, A, Stoll, T. 2020. Accrual of atherosclerotic vascular events in a multicentre inception SLE cohort. :. PubMed PMID:32515554

Mes, SW, van Velden, FHP, Peltenburg, B, Peeters, CFW, Te Beest, DE, van de Wiel, MA, Mekke, J, Mulder, DC, Martens, RM, Castelijns, JA, Pameijer, FA, de Bree, R, Boellaard, R, Leemans, CR, Brakenhoff, RH, de Graaf, P. 2020. Outcome prediction of head and neck squamous cell carcinoma by MRI radiomic signatures. Eur Radiol :. PubMed PMID:32500196

Larsson, SC, Gill, D, Mason, AM, Jiang, T, Bäck, M, Butterworth, AS, Burgess, S. 2020. Lipoprotein(a) in Alzheimer, Atherosclerotic, Cerebrovascular, Thrombotic, and Valvular Disease: Mendelian Randomization Investigation. Circulation 141:1826-1828. PubMed PMID:32479194

Bottolo, L, Miller, S, Johnson, SR. 2020. Sphingolipid, fatty acid and phospholipid metabolites are associated with disease severity and mTOR inhibition in lymphangioleiomyomatosis. Thorax :. PubMed PMID:32467337

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Additional Material

We also have a repository of Reports, Published Material, Pre-prints and Technical Reports in our Additional Material webpage.