Email Address: L.Sharples@leeds.ac.uk
Other Research Theme Collaborations: DART
Linda Sharples is currently a Visiting Scientist at the MRC Biostatistics Unit (BSU).
Until September 2013 Linda led a programme of research in statistical methods for health technology assessment at the BSU, with particular emphasis on trials of surgical procedures, diagnostic strategies and service delivery. These methods were motivated by, and fed back into, observational and experimental studies and decision models arising from a long-standing collaboration with clinicians at Papworth Hospital in Cambridge.
Linda Sharples currently holds a position as Professor of Statistics at the Leeds Clinical Trials Research Unit. There she leads the Comprehensive Health Research Division which has a focus on musculoskeletal, cardiovascular, skin and dental trials. She has a first class honours degree in Mathematics and a PhD in Statistics, both from Nottingham University.
Selected PapersPapachristofi O; Mackay JH; Powell SJ; Nashef SA; Sharples L. (2014)Impact of the anesthesiologist and surgeon on cardiac surgical outcomes.
J Cardiothorac Vasc Anesth 28: (1), 103-109
Thom H; West NE; Hughes V; Dyer M; Buxton M; Sharples LD; Jackson CH; Crean AM; CECaT study group. (2014)Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: mid-term outcomes from the CECaT randomised controlled trial.
BMJ Open 4: (2), e003419
Nashef SA; Sharples LD. (2013)Editorial comment: Pride without prejudice: EuroSCORE II, the STS score and the high-risk patient subset.
Eur J Cardiothorac Surg 44: (6), 1012
Gjorgjimajkoska O; Kosmoliaptsis V; Sharples LD; Chaatzizacharias N; Peacock S; Bradley JA; Taylor CJ. (2013)Donor HLA mismatch determines the risk of HLA locus-specific sensitisation and access to repeat kidney transplantation following primary allograft failure.
Transplant International 26: 78-78
Gjorgjimajkoska O; Mallon D; Sharples LD; Jayaraman J; Traherne J; Trowsdale J; Mulder A; Claas F; Bolton EM; Taylor CJ; Bradley JA; Lewis C; Parmar J; Pettigrew GJ. (2013)Killer immunoglobulin-like receptor (KIR)-Ligand mismatches do not affect the duration of peripheral blood donor CD4 T-cell chimerism following lung transplantation.
Transplant International 26: 179-179