Current Vacancies

Currently 71 scientists and support staff make up the MRC Biostatistics Unit, with about 58 directly carrying out research, in four distinctive research theme groups led by ten Programme Leaders. Around 16 of the researchers are PhD students – see PhD at BSU for postgraduate opportunities.

The BSU places a strong emphasis on training the statisticians of the future. Through our Career Development and PhD programmes we are committed to filling the strategic skills gap in statistics identified by Professor Adrian Smith FRS in 2010.

Furthermore the Unit provides a unique environment in which researchers apply their statistical and mathematical knowledge to real data to solve real problems.

For more information about the Unit, and the attractive environment in which we work, please visit our Working at BSU section.


Job Title: Fellowship-track
Salary: Band 4: £27,355 - £35,405 per annum / Band 3: £37,024 - £43,520 per annum
Band: Band 4 / Band 3
Contract Type: Fixed term for 2 years
Hours: Full-time, 36 hours per week OR part-time (minimum 21.6 hours per week)
Closing Date: 19th June 2016

More details / Apply

Overall purpose:

To lead one or more projects which fall within the Unit’s current research which is categorised within 4 broad themes: (i) design and analysis of randomised trials, (ii) evidence synthesis methods to inform health, (iii) methods for the analysis of complex longitudinal data and for stratified medicine, and (iv) modelling and inference in statistical genomics.

To play a major role in the work of the research group, through the conduct of research, introduction of new ideas, dissemination of research results, support and training of others.

In addition, the post-holder will use approximately 40% of their time to develop and progress their personal fellowship applications. These must be made to recognised research funding bodies and build on the individual’s research programme.

Main duties / key responsibilities:

Main duties

Under the general leadership of the Programme Leader, to be responsible for all aspects of the research projects, including defining the direction of the work, conducting the research, analysing the data, preparing the work for publication and disseminating the results at meetings.

To develop and progress personal fellowship applications, to recognised research funding bodies, building on the individual’s research programme.

To present their work at seminars within the Unit and at external meetings.

To contribute to unit-wide discussions on developments within the Unit, particularly in the use of new techniques.

To identify, develop and apply a broad range of techniques to pursue the research objectives.

To keep up to date with developments in the field, proposing or implementing changes of direction as necessary.

To prepare the research for publication.

To work in collaboration with others to achieve joint research projects.

To train students, post docs and others, and line management of group members where appropriate.

To contribute to the MRC’s engagement with the public and in the translation of research findings into improvements in health care.

Key Responsibilities

The key responsibility is to undertake cutting edge research, aimed at key questions within the remit of the research group.  They will be expected to provide the intellectual energy and independent thinking necessary to deliver the research and to play a major role in shaping the overall aims and success of the group.

While some advice will be available from others in the Unit, the post holder will be expected to have the skill and understanding to be able to act independently in solving problems, many of which may require novel approaches.  This will require the integration of different activities to ensure the successful delivery of the research projects.

Other responsibilities are:

To be aware of existing literature and current issues; solve problems that entail novel approaches and the integration of different ideas and activities to ensure the successful completion of the research project.

To interact effectively with a wide range of staff, students and others to ensure the smooth running of the research group.

To disseminate research results through publication of research papers.

To present the work at national and international scientific meetings and conferences.

To maintain external collaborations where these will contribute to the pursuit of the research.

To ensure the research is conducted in accordance with good practice and in compliance with local policies and legal requirements.

To identify opportunities for personal fellowships, and to apply for external grants where appropriate.

Where line management responsibilities are undertaken, these responsibilities, including staff development and performance management, should be applied in accordance with the MRC’s policies and procedures. Training will be provided if required.

Working relationships:

The postholder will report to a Programme Leader within the BSU and will liaise with other Research Support staff, post-doctoral scientists and students within the Group and across the Unit and with external collaborators.

Successful candidates will be appointed to a two-year fixed term position at either Band 4 (£27,355 - £35,405) or Band 3 (£37,024 - £43,520), depending on their level of experience. This salary is supported by a flexible pay and reward policy, 30 days annual leave entitlement, and an optional MRC final salary Pension Scheme.

To view and download the full Job Description for the Investigator Statistician (Band 4), click here: Investigator Statistician - Job Description Person Specification - Fellowship-track

To view and download the full Job Description for the Senior Investigator Statistician (Band 3), click here: Senior Investigator Statistician - Job Description Person Specification - Fellowship track

How to Apply:

To apply, please complete an Application Form and forward your CV and cover letter to: recruitment@mrc-bsu.cam.ac.uk quoting Reference Number MRCBSU00010.

To download an Application Form, click here: Application Form

Closing date for applications: 19th June 2016

This position is subject to pre-employment screening
The Medical Research Council is an Equal Opportunities Employer

 

Job Title: Postdoctoral Statistician
Salary: £27,355 - £30,486 per annum
Band: Band 4
Contract Type: Fixed Term until 31st March 2019
Hours: Full time, 36 hours per week
Closing Date: 13th June
Interview Date:
28th June

More details / Apply

Overall purpose:

To work within a programme led by Dr Adrian Mander in the area of adaptive clinical trial design.

The programme has several researchers in various aspects of adaptive trials such as using historical data in trial designs, multi-arm multi-stage trials, dose-escalation designs for single and combination products, group sequential crossover designs, multi-arm bandit designs and many more.

This post will investigate biomarker-driven designs in the area of dementia research. This project uses the information obtained from the DPUK grant that is collecting information from various UK observational studies. The next step will be to use the findings from the modelling tasks and integrate them into a plan of trials that aim to maximise the chance of finding promising medications. The work plans to review the current state of the literature and to see how these designs may translate to dementia trials and also to investigate novel approaches to tailor designs within this field.

Main duties / key responsibilities:

Main duties

  • To undertake research aimed at developing new trial designs tailored to dementia research
  • To identify, develop and apply a broad range of techniques to pursue the research objectives
  • To present scientific work at seminars within the Unit and at external meetings
  • To contribute to Unit-wide discussions on developments within the field
  • To draft scientific papers, and contribute to the overall preparation of research for publication
  • To contribute to the Unit’s mission in the public engagement of science, and the translation of research findings into improvements in health care
  • To assist in the training of PhD students and others.

Key Responsibilities

Within the overall direction of the programme of the group and the remit of the project, and in discussion with the group leader, the post holder will make a significant input into determining the direction of the project with a 3 year lifespan.

To plan their own work and objectives on a 12 month basis and will manage their experimental work within the project along with their supervisor.

To work with supervision to identify, develop, modify and apply the necessary techniques to achieve the goals of the project.

To identify, develop and apply a broad range of techniques to pursue the research objectives.

To ensure the research is carried in accordance with good practice and in compliance with local polices and legal requirements.

To interact effectively with a wide range of staff, students and others to ensure the smooth running of the research group.

To enhance their research and generic skills through a tailored development programme.

Working relationships:

The postholder will report to Dr Adrian Mander and will interact and collaborate with other postdoctoral scientists, research support staff and students in the Group and across the Unit, and with external Groups as necessary.

Additional information:

This is a three-year training and development position.  The MRC Post-Doctoral Training scheme provides fixed term formal training and development opportunities for post-doctoral scientists in need of research and transferable skills training in order to establish themselves as productive research scientists. Researchers taking part in this scheme will sign a training contract and be expected to fulfil a formal training programme during their employment. Postdocs will receive allowances at certain stages of their training contract. Participants of the scheme will not be eligible for redundancy compensation payments at the end of their training period.

Starting salary will be in the range of £28,007 - £30,791 per annum, supported by a flexible pay and reward policy, 30 days annual leave entitlement, and an optional MRC final salary Pension Scheme.

To view and download the full Job Description, click here: Postdoc - Job Description Person Specification_DPUK

How to Apply:

To apply, please complete an Application Form and forward your CV and cover letter to: recruitment@mrc-bsu.cam.ac.uk quoting Reference Number MRCBSU00011.

To download an Application Form, click here: Application Form

Closing date for applications: 13th June 2016

For an informal discussion about thIs post please contact james.wason@mrc-bsu.cam.ac.uk

For information on the DPUK, please visit http://www.dementiasplatform.uk

This position is subject to pre-employment screening
The Medical Research Council is an Equal Opportunities Employer

 

Job Title: Postdoctoral Statistician
Salary: £28,007 - £32,648 per annum
Band: Band 4
Contract Type: Fixed Term - 3 years
Hours: Full-time, 36 hours per week
Closing Date: 15th June
Interview Date:
29th June

More details / Apply

Overall purpose:

To work within a programme aimed at using genomics to improve understanding of autoimmune diseases. Specifically to undertake research to investigate the effects of genetic variation on gene regulation in primary human immune cells.  We need better understanding of which variants regulate which genes in which cells, in order to properly interpret genetic associations with autoimmune diseases.

This project will develop latent variable regression models to relate chromatin changes at putative regulatory variants to expression changes at genes linked to them through Hi-C experiments which describe the 3D folding of DNA in cell nuclei.  Latent variable methods are required because of the different scales of resolution of the linking data (~4000bp) and the chromatin state data (~20bp).  Once developed, these models will be used to address fundamental genomic questions of enhancer redundancy “buffering” in the regulation of gene transcription and predict the effects of disease associated genetic variants on gene regulation.

Main duties / key responsibilities:

Main duties

  • To undertake research aimed at developing latent variable regression models for genomic regulation and applying them to address questions of biological importance and disease relevance.
  • To identify, develop and apply a broad range of techniques to pursue the research objectives
  • To present scientific work at seminars within the Unit and at external meetings
  • To contribute to Unit-wide discussions on developments within the field
  • To draft scientific papers, and contribute to the overall preparation of research for publication
  • To contribute to the Unit’s mission in the public engagement of science, and the translation of research findings into improvements in health care
  • To assist in the training of PhD students and others.

Key Responsibilities

To make a significant input into determining the direction of the project, within the overall direction of the programme of the group and the remit of the project, and in discussion with the group leader.

To plan their own work and objectives on a 12 month basis and to manage their experimental work within the project along with their supervisor.

To work with limited supervision to identify, develop, modify and apply the necessary techniques to achieve the goals of the project.

To identify, develop and apply a broad range of techniques to pursue the research objectives.

To ensure the research is carried out in accordance with good practice and in compliance with local polices and legal requirements.

To interact effectively with a wide range of staff, students and others to ensure the smooth running of the research group.

To enhance their research and generic skills through a tailored development programme.

Working relationships:

The postholder will report to Dr Chris Wallace and will interact and collaborate with other postdoctoral scientists, research support staff and students in the Group and across the Unit, and with external Groups as necessary.

Additional information:

This is a three-year training and development position.  The MRC Post-Doctoral Training scheme provides fixed term formal training and development opportunities for post-doctoral scientists in need of research and transferable skills training in order to establish themselves as productive research scientists. Researchers taking part in this scheme will sign a training contract and be expected to fulfil a formal training programme during their employment. Postdocs will receive allowances at certain stages of their training contract. Participants of the scheme will not be eligible for redundancy compensation payments at the end of their training period.

To view and download the full Job Description, click here: Postdoc - Job Description Person Specification_Chris Wallace

How to Apply:

To apply, please complete an Application Form and forward your CV and cover letter to: recruitment@mrc-bsu.cam.ac.uk quoting Reference Number MRCBSU00009.

To download an Application Form, click here: Application Form

Closing date for applications: 15th June 2016

This position is subject to pre-employment screening
The Medical Research Council is an Equal Opportunities Employer

 

MRC welcomes applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As users of the “Two Ticks” disability symbol, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.

For general MRC employment enquiries please see Working for the MRC or contact:
RCUK Shared Service Centre.
Tel: 01793 867000, and select option 3 for HR
E-mail: HR@ssc.rcuk.ac.uk