Summary
I am a Research Associate in biostatistics, working on applications in haematology and transfusion medicine with Dr William Astle, as part of the Haem-Match project. Haem-Match aims to provide blood for transfusion that is more precisely matched to patients’ blood groups, and optimally allocate units of blood in order to maintain blood stocks and minimise the risk of adverse reaction events.
I enjoy working on interdisciplinary projects. My main research interests are: high-dimensional data, missing values & imputation methods, (prote)omics data, genetic epidemiology, medical applications.
Previously, I was a postdoctoral researcher in genetic epidemiology, working working on new methodologies for the detection of gene-environment interactions in cancer studies, with Dr Olivier Bouaziz, in the MAP5 Lab at Paris Cité University, France.
I did my PhD at the University of Strasbourg, France, on developing new statistical methodologies for quantitative proteomics data analysis.
- Website: https://mariechion.github.io/
- Google Scholar: https://scholar.google.com/citations?user=A9icRFkAAAAJ&hl=fr
- OrcID: https://orcid.org/0000-0001-8956-8388
Selected Papers
Chion, M., Carapito, C. & Bertrand, F (2023) Towards a more accurate differential analysis of multiple imputed proteomics data with mi4limma. Methods in Molecular Biology, Humana Press Vol. 2426:
Chion, M., Carapito, C. & Bertrand, F (2022) Accounting for multiple imputation-induced variability for differential analysis in mass spectrometry-based label-free quantitative proteomics. PLOS Computational Biology 18(8): e1010420:
Bons, J., Husson, G., Chion, M., Bonnet, M., Maumy‐Bertrand, M., Delalande, F., Cianférani, S., Bertrand, F., Picard, B. & Carapito, C (2021) Combining label‐free and label‐based accurate quantifications with SWATH‐MS: comparison with SRM and PRM for the evaluation of bovine muscle type effects. Proteomics.
Muller, L., Fornecker, L., Chion, M., Van Dorsselaer, A., Cianférani, S., Rabilloud, T. & Carapito, C (2018) Extended investigation of tube-gel sample preparation: a versatile and simple choice for high throughput quantitative proteomics. Scientific Reports 8:8260.